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A Link between Virulence and Homeostatic Responses to Hypoxia during Infection by the Human Fungal Pathogen Cryptococcus neoformans

Fungal pathogens of humans require molecular oxygen for several essential biochemical reactions, yet virtually nothing is known about how they adapt to the relatively hypoxic environment of infected tissues. We isolated mutants defective in growth under hypoxic conditions, but normal for growth in n...

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Autors principals: Chun, Cheryl D, Liu, Oliver W, Madhani, Hiten D
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1803011/
https://ncbi.nlm.nih.gov/pubmed/17319742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030022
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