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Global analysis of microRNA target gene expression reveals that miRNA targets are lower expressed in mature mouse and Drosophila tissues than in the embryos

MicroRNAs (miRNAs) are non-coding small RNAs of ∼22 nt that regulate the gene expression by base pairing with target mRNAs, leading to mRNA cleavage or translational repression. It is currently estimated that miRNAs account for ∼1% of predicted genes in higher eukaryotic genomes and that up to 30% o...

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Bibliografiske detaljer
Main Authors: Yu, Zhenbao, Jian, Zhaofeng, Shen, Shi-Hsiang, Purisima, Enrico, Wang, Edwin
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802562/
https://ncbi.nlm.nih.gov/pubmed/17158157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1032
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