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Use of modified U1 snRNAs to inhibit HIV-1 replication

Control of RNA processing plays a central role in regulating the replication of HIV-1, in particular the 3′ polyadenylation of viral RNA. Based on the demonstration that polyadenylation of mRNAs can be disrupted by the targeted binding of modified U1 snRNA, we examined whether binding of U1 snRNAs t...

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Detalles Bibliográficos
Main Authors: Sajic, R., Lee, K., Asai, K., Sakac, D., Branch, D. R., Upton, C., Cochrane, A.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2007
Assuntos:
RNA
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802557/
https://ncbi.nlm.nih.gov/pubmed/17158512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1022
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