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Use of modified U1 snRNAs to inhibit HIV-1 replication

Control of RNA processing plays a central role in regulating the replication of HIV-1, in particular the 3′ polyadenylation of viral RNA. Based on the demonstration that polyadenylation of mRNAs can be disrupted by the targeted binding of modified U1 snRNA, we examined whether binding of U1 snRNAs t...

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Détails bibliographiques
Auteurs principaux: Sajic, R., Lee, K., Asai, K., Sakac, D., Branch, D. R., Upton, C., Cochrane, A.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2007
Sujets:
RNA
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802557/
https://ncbi.nlm.nih.gov/pubmed/17158512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1022
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