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Use of modified U1 snRNAs to inhibit HIV-1 replication

Control of RNA processing plays a central role in regulating the replication of HIV-1, in particular the 3′ polyadenylation of viral RNA. Based on the demonstration that polyadenylation of mRNAs can be disrupted by the targeted binding of modified U1 snRNA, we examined whether binding of U1 snRNAs t...

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Main Authors: Sajic, R., Lee, K., Asai, K., Sakac, D., Branch, D. R., Upton, C., Cochrane, A.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2007
主題:
RNA
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802557/
https://ncbi.nlm.nih.gov/pubmed/17158512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1022
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