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Selective inhibition by rottlerin of macropinocytosis in monocyte-derived dendritic cells

We present here the analysis of fluid-phase endocytosis (FPE) in human blood monocytes and monocyte-derived dendritic cells (MDDC) facilitated by our serendipitous identification of rottlerin as an efficient inhibitor of dendritic cell FPE (IC(50) of 0·4 µm). Rottlerin was found to be an excellent t...

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Detalhes bibliográficos
Main Authors: Sarkar, Kakali, Kruhlak, Michael J, Erlandsen, Stanley L, Shaw, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802442/
https://ncbi.nlm.nih.gov/pubmed/16313365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02253.x
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