Construction and characterization of a humanized anti-human CD3 monoclonal antibody 12F6 with effective immunoregulation functions

12F6 is a murine anti-human CD3 monoclonal antibody, which competes with OKT3 for binding to human T cells and possesses more effective T-cell suppression and activation properties compared to OKT3. It thus exhibits the potential to be developed as an immunoregulation agent for manipulating T-cell f...

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Bibliographic Details
Main Authors: Li, Bohua, Wang, Hao, Dai, Jianxin, Ji, Junjie, Qian, Weizhu, Zhang, Dapeng, Hou, Sheng, Guo, Yajun
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2005
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802437/
https://ncbi.nlm.nih.gov/pubmed/16313362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02247.x
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