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CT60 genotype does not affect CTLA-4 isoform expression despite association to T1D and AITD in northern Sweden

BACKGROUND: Polymorphisms in and around the CTLA-4 gene have previously been associated to T1D and AITD in several populations. One such single nucleotide polymorphism (SNP), CT60, has been reported to affect the expression level ratio of the soluble (sCTLA-4) to full length CTLA-4 (flCTLA-4) isofor...

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Detalhes bibliográficos
Main Authors: Mayans, Sofia, Lackovic, Kurt, Nyholm, Caroline, Lindgren, Petter, Ruikka, Karin, Eliasson, Mats, Cilio, Corrado M, Holmberg, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802068/
https://ncbi.nlm.nih.gov/pubmed/17280620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-8-3
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