Elimination of multicopy plasmid R6K by bleomycin.

Bleomycin eliminated multicopy plasmid R6K from growing cells of Escherichia coli AB1157 but failed to cure either of the low-copy plasmids R1 or R46. Measurements of R6K-encoded beta-lactamase and of covalently closed plasmid DNA indicated that the drug causes a progressive reduction in plasmid cop...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Attfield, P V, Pinney, R J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1985
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180205/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2411218/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.6.985
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