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Determination of inhibitory concentrations of antiviral agents in cell culture by use of an enzyme immunoassay with virus-specific, peroxidase-labeled monoclonal antibodies.

An enzyme immunoassay (EIA) to determine 50% inhibitory concentrations of drugs which suppress Semliki Forest virus replication is described. Inhibition of virus replication was measured in L-cells, seeded as monolayers in 96-well plates by use of horseradish peroxidase-labeled monoclonal antibodies...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: van Tiel, F H, Boere, W A, Harmsen, T, Kraaijeveld, C A, Snippe, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1985
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180155/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3925876/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.5.802
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