Linkage studies on Gilles de la Tourette syndrome: what is the strategy of choice?

For a linkage study it is important to ascertain family material that is sufficiently informative. The statistical power of a linkage sample can be determined via computer simulation. For complex traits uncertain parameters such as incomplete penetrance, frequency of phenocopies, gene frequency and...

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Bibliografiske detaljer
Main Authors: Heutink, P, van de Wetering, B J, Pakstis, A J, Kurlan, R, Sandor, P, Oostra, B A, Sandkuijl, L A
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801534/
https://ncbi.nlm.nih.gov/pubmed/7668273
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