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The fragile X premutation in carriers and its effect on mutation size in offspring.

The pattern of inheritance in the fragile X (fra(X)) mutation follows a multistage intergenerational process in which the premutation evolves into the full mutation and the characteristic phenotype of the fra(X) syndrome after passing through oogenesis or a postzygotic event. Findings from our multi...

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Autori principali: Fisch, G S, Snow, K, Thibodeau, S N, Chalifaux, M, Holden, J J, Nelson, D L, Howard-Peebles, P N, Maddalena, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801463/
https://ncbi.nlm.nih.gov/pubmed/7726171
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