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Covalent binding of moxalactam to cephalosporinase of Citrobacter freundii.

The inhibition of Citrobacter freundii cephalosporinase activity by moxalactam is shown to be due to the formation of a transiently stable covalent complex, probably acyl enzyme. The covalent complex formed was identified by coelution of [14C] moxalactam with the enzyme by using Sephadex G-25 gel fi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Murakami, K, Yoshida, T
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180142/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3874595/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.5.727
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