A gene that regulates DNA replication in response to DNA damage is located on human chromosome 4q.

Inhibition of replicative DNA synthesis following gamma-irradiation is observed in eukaryotic cells but is defective in cells derived from patients with the cancer-prone inherited disorder ataxia-telangiectasia (A-T) and in A-T-like Chinese hamster cell mutants. Chinese hamster cells show a less pro...

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Bibliographic Details
Main Authors: Verhaegh, G W, Jongmans, W, Jaspers, N G, Natarajan, A T, Oshimura, M, Lohman, P H, Zdzienicka, M Z
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801354/
https://ncbi.nlm.nih.gov/pubmed/7485160
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