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Likelihood methods for locating disease genes in nonequilibrium populations.

Until recently, attempts to map disease genes on the basis of population associations with linked markers have been based on expected values of linkage disequilibrium. These methods suffer from the large variances imposed on disequilibrium measures by the evolutionary process, but a more serious pro...

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Hlavní autoři: Kaplan, N L, Hill, W G, Weir, B S
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801340/
https://ncbi.nlm.nih.gov/pubmed/7825575
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