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Autosomal dominant familial spastic paraplegia: reduction of the FSP1 candidate region on chromosome 14q to 7 cM and locus heterogeneity.

Three large pedigrees of German descent with autosomal dominant "pure" familial spastic paraplegia (FSP) were characterized clinically and genetically. Haplotype and linkage analyses, with microsatellites covering the FSP region on chromosome 14q (locus FSP1), were performed. In pedigree W...

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Bibliografiske detaljer
Main Authors: Gispert, S, Santos, N, Damen, R, Voit, T, Schulz, J, Klockgether, T, Orozco, G, Kreuz, F, Weissenbach, J, Auburger, G
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801298/
https://ncbi.nlm.nih.gov/pubmed/7825576
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