Localization of an Ataxia-Telangiectasia Gene to an −500-kb Interval on Chromosome 11q23.1: Linkage Analysis of 176 Families by an International Consortium

We describe a 20-point linkage analysis map of chromosome 11q22-23 that is based on genotyping 249 families (59 CEPH and 190 A-T). Monte Carlo linkage analyses of 176 ataxia-telangiectasia (A-T) families localizes the major A-T locus to the region between S1819(A4) and S1818(A2). When seven nonlinki...

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Autori principali: Lange, Ethan, Borresen, Anna-Lise, Chen, Xiaoguang, Chessa, Luciana, Chiplunkar, Sujata, Concannon, Patrick, Dandekar, Sugandha, Gerken, Steven, Lange, Kenneth, Liang, Teresa, McConville, Carmel, Polakow, Jeff, Porras, Oscar, Rotman, Galit, Sanal, Ozden, Sheikhavandi, Sepideh, Shiloh, Yosef, Sobel, Eric, Taylor, Malcolm, Telatar, Milhan, Teraoka, Sharon, Tolun, Aslihan, Udar, Nitin, Uhrhammer, Nancy, Vanagaite, Lina, Wang, Zhijun, Wapelhorst, Beth, Wright, Jocyndra, Yang, Huan-Ming, Yang, Lan, Ziv, Yael, Gatti, Richard A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801232/
https://ncbi.nlm.nih.gov/pubmed/7611279
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