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Multipoint linkage analysis using sib pairs: an interval mapping approach for dichotomous outcomes.
I propose an interval mapping approach suitable for a dichotomous outcome, with emphasis on samples of affected sib pairs. The method computes a lod score for each of a set of locations in the interval between two flanking markers and takes as its estimate of trait-locus location the maximum lod sco...
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| Autore principale: | |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1995
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1801153/ https://ncbi.nlm.nih.gov/pubmed/7887435 |
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