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Verification of phylogenetic predictions in vivo and the importance of the tetraloop motif in a catalytic RNA

M1 RNA, the catalytic subunit of Escherichia coli RNase P, forms a secondary structure that includes five sequence variants of the tetraloop motif. Site-directed mutagenesis of the five tetraloops of M1 RNA, and subsequent steady-state kinetic analysis in vitro, with different substrates in the pres...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Krummel, Daniel A. Pomeranz, Altman, Sidney
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1999
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500154/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11200
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