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Short-term induction and long-term suppression of HPV16 oncogene silencing by RNA interference in cervical cancer cells

RNA interference-mediated gene silencing has the potential to block gene expression. A synthetic double-stranded (ds) siRNA based on a sequence motif of 21 nts from human papillomavirus 16 (HPV16) E6E7 bicistronic RNA was found to be a potent small interfering RNA (siRNA) that suppresses expression...

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Detalhes bibliográficos
Main Authors: Tang, Shuang, Tao, Mingfang, McCoy, J. Philip, Jr, Zheng, Zhi-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800826/
https://ncbi.nlm.nih.gov/pubmed/16369495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209244
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