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MEKK1 Mediates the Ubiquitination and Degradation of c-Jun in Response to Osmotic Stress

c-Jun, a major transcription factor in the activating protein 1 family of regulatory proteins, is activated by many physiologic and pathological stimuli. We show here that c-Jun was downregulated in response to osmotic stress via ubiquitination-dependent degradation by the PHD/RING finger domain of...

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Bibliografski detalji
Glavni autori: Xia, Yan, Wang, Ji, Xu, Shuichan, Johnson, Gary L., Hunter, Tony, Lu, Zhimin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800814/
https://ncbi.nlm.nih.gov/pubmed/17101801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01355-06
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