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MEKK1 Mediates the Ubiquitination and Degradation of c-Jun in Response to Osmotic Stress
c-Jun, a major transcription factor in the activating protein 1 family of regulatory proteins, is activated by many physiologic and pathological stimuli. We show here that c-Jun was downregulated in response to osmotic stress via ubiquitination-dependent degradation by the PHD/RING finger domain of...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1800814/ https://ncbi.nlm.nih.gov/pubmed/17101801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01355-06 |
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