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Regulation of Commissureless by the Ubiquitin Ligase DNedd4 Is Required for Neuromuscular Synaptogenesis in Drosophila melanogaster

Muscle synaptogenesis in Drosophila melanogaster requires endocytosis of Commissureless (Comm), a binding partner for the ubiquitin ligase dNedd4. We investigated whether dNedd4 and ubiquitination mediate this process. Here we show that Comm is expressed in intracellular vesicles in the muscle, wher...

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Detalhes bibliográficos
Main Authors: Ing, Bryant, Shteiman-Kotler, Alina, Castelli, MaryLisa, Henry, Pauline, Pak, Youngshil, Stewart, Bryan, Boulianne, Gabrielle L., Rotin, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800811/
https://ncbi.nlm.nih.gov/pubmed/17074801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00463-06
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