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In Trypanosoma brucei RNA Editing, TbMP18 (Band VII) Is Critical for Editosome Integrity and for both Insertional and Deletional Cleavages

In trypanosome RNA editing, uridylate (U) residues are inserted and deleted at numerous sites within mitochondrial pre-mRNAs by an ∼20S protein complex that catalyzes cycles of cleavage, U addition/U removal, and ligation. We used RNA interference to deplete TbMP18 (band VII), the last unexamined ma...

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Bibliografski detalji
Glavni autori: Law, Julie A., O'Hearn, Sean, Sollner-Webb, Barbara
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800803/
https://ncbi.nlm.nih.gov/pubmed/17101787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01460-06
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