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In Trypanosoma brucei RNA Editing, TbMP18 (Band VII) Is Critical for Editosome Integrity and for both Insertional and Deletional Cleavages

In trypanosome RNA editing, uridylate (U) residues are inserted and deleted at numerous sites within mitochondrial pre-mRNAs by an ∼20S protein complex that catalyzes cycles of cleavage, U addition/U removal, and ligation. We used RNA interference to deplete TbMP18 (band VII), the last unexamined ma...

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Bibliografische gegevens
Hoofdauteurs: Law, Julie A., O'Hearn, Sean, Sollner-Webb, Barbara
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800803/
https://ncbi.nlm.nih.gov/pubmed/17101787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01460-06
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