Integrity of the Mod(mdg4)-67.2 BTB Domain Is Critical to Insulator Function in Drosophila melanogaster

The Drosophila gypsy insulator contains binding sites for the Suppressor of Hairy-wing [Su(Hw)] protein. Enhancer and silencer blocking require Su(Hw) recruitment of Mod(mdg4)-67.2, a BTB/POZ domain protein that interacts with Su(Hw) through a carboxyl-terminal acidic domain. Here we conducted mutat...

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Main Authors: Golovnin, Anton, Mazur, Alexander, Kopantseva, Marina, Kurshakova, Maria, Gulak, Pavel V., Gilmore, Brian, Whitfield, William G. F., Geyer, Pamela, Pirrotta, Vincenzo, Georgiev, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800699/
https://ncbi.nlm.nih.gov/pubmed/17101769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00795-06
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