Combining Sperm Typing and Linkage Disequilibrium Analyses Reveals Differences in Selective Pressures or Recombination Rates Across Human Populations

A previous polymorphism survey of the type 2 diabetes gene CAPN10 identified a segment showing an excess of polymorphism levels in all population samples, coinciding with localized breakdown of linkage disequilibrium (LD) in a sample of Hausa from Cameroon, but not in non-African samples. This raise...

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Main Authors: Clark, Vanessa J., Ptak, Susan E., Tiemann, Irene, Qian, Yudong, Coop, Graham, Stone, Anne C., Przeworski, Molly, Arnheim, Norman, Rienzo, Anna Di
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2007 by the Genetics Society of America 2007
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Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800598/
https://ncbi.nlm.nih.gov/pubmed/17151245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.064964
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