Ciprofloxacin penetration into extravascular spaces in a rabbit model.

Ciprofloxacin penetration into extravascular spaces was studied in a rabbit Visking chamber model. The drug was administered (7 mg/kg) intramuscularly every 4 h for eight doses. Peak and trough drug levels by dose 8 were 1.3 and 0.35 micrograms/ml in serum and 0.61 and 0.50 micrograms/ml in extravas...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Nichol, K L, Peterson, L R, Fasching, C E, Gerding, D N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1984
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180055/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6524907/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.26.6.935
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