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Pharmacokinetics of cefotiam in patients with impaired renal function and in those undergoing hemodialysis.

The pharmacokinetics of cefotiam were studied after a single intravenous 1.0-g dose to 18 subjects grouped according to their creatinine clearances (CLCR); CLCR was above 75, 75 to 20, and below 20 ml/min per 1.73 m2 in groups 1, 2, and 3, respectively. Cefotiam obeyed two-compartment model kinetics...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Konishi, K, Ozawa, Y
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179986/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6097172/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.26.5.647
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