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Suppression of respiratory syncytial virus infection in cotton rats by bis(5-amidino-2-benzimidazolyl)methane.

Intraperitoneal administration of bis(5-amidino-2-benzimidazolyl)methane at well-tolerated daily doses of 25 mg/kg subsequent to challenge and for 3 days thereafter effected over a 1-log reduction in the amount of virus recovered from lungs of cotton rats inoculated intratracheally with respiratory...

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Published in:Antimicrob Agents Chemother
Main Authors: Tidwell, R R, Geratz, J D, Clyde, W A, Rosenthal, K U, Dubovi, E J
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1984
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179971/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6393863/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.26.4.591
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