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Determination of imipenem and cilastatin in serum by high-pressure liquid chromatography.

Imipenem and cilastatin concentrations in serum were determined by using reverse-phase high-pressure liquid chromatography. Serum samples were stabilized with 0.5 M morpholineethanesulfonic acid buffer (pH 6.0) and subjected to ultrafiltration before chromatography. The elution solvent consisted of...

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Publicado en:Antimicrob Agents Chemother
Principais autores: Myers, C M, Blumer, J L
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1984
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179921/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6591852/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.26.1.78
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