Significance of Pretreatment Analysis of Hepatitis C Virus Genotype 1b Hypervariable Region 1 Sequences To Predict Antiviral Outcome

The heterogeneity of hypervariable region 1 (HVR1), located at the amino terminus of the E2 envelope, may be involved in resistance to alpha interferon (IFN-α) treatment. We investigated whether peculiar HVR1 domain profiles before treatment were associated with the maintenance of sensitivity or the...

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Bibliografiske detaljer
Main Authors: Gaudy, Catherine, Moreau, Alain, Veillon, Pascal, Temoin, Stephanie, Lunel, Francoise, Goudeau, Alain
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Virology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC179854/
https://ncbi.nlm.nih.gov/pubmed/12904364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.41.8.3615-3622.2003
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