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Elevated oxidative stress in erythrocytes due to a SOD1 deficiency causes anaemia and triggers autoantibody production

Reactive oxygen species are involved in the aging process and diseases. Despite the important role of Cu/Zn SOD (superoxide dismutase) encoded by SOD1, SOD1(−/−) mice appear to grow normally under conventional breeding conditions. In the present paper we report on a novel finding showing a distinct...

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Detalhes bibliográficos
Main Authors: Iuchi, Yoshihito, Okada, Futoshi, Onuma, Kunishige, Onoda, Tadashi, Asao, Hironobu, Kobayashi, Masanobu, Fujii, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798435/
https://ncbi.nlm.nih.gov/pubmed/17059387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061386
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