The binding of lupus‐derived autoantibodies to the C‐terminal peptide (83–119) of the major SmD1 autoantigen can be mediated by double‐stranded DNA and nucleosomes

OBJECTIVES: To evaluate the binding of lupus‐derived autoantibodies, double‐stranded DNA and nucleosomes to the positively charged C‐terminal SmD1(residues 83–119) peptide and the full‐length SmD protein. METHODS: The binding of lupus‐derived monoclonal antibodies, sera from patients with systemic l...

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Autors principals: Dieker, J W, Van Bavel, C C, Riemekasten, G, Berden, J H, van der Vlag, J
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2006
Matèries:
Concise Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798367/
https://ncbi.nlm.nih.gov/pubmed/16540553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2005.043992
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