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Polymorphism at position +896 of the toll‐like receptor 4 gene interferes with rapid response to treatment in rheumatoid arthritis

The aim of this study was to determine whether the +896 A→G substitution of the Toll‐like receptor 4 (TLR4) gene, causing the Asp299→Gly change in the extracellular domain of TLR4, influences treatment response in recent‐onset rheumatoid arthritis. 169 patients with rheumatoid arthritis were genotyp...

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Detalhes bibliográficos
Main Authors: Kuuliala, K, Orpana, A, Leirisalo‐Repo, M, Kautiainen, H, Hurme, M, Hannonen, P, Korpela, M, Möttönen, T, Paimela, L, Puolakka, K, Karjalainen, A, Repo, H
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798301/
https://ncbi.nlm.nih.gov/pubmed/16606645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.055137
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