Finnish HLA studies confirm the increased risk conferred by HLA‐B27 homozygosity in ankylosing spondylitis

OBJECTIVE: To determine the influence of HLA‐B27 homozygosity and HLA‐DRB1 alleles in the susceptibility to, and severity of, ankylosing spondylitis in a Finnish population. METHODS: 673 individuals from 261 families with ankylosing spondylitis were genotyped for HLA‐DRB1 alleles and HLA‐B27 heteroz...

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Detalhes bibliográficos
Main Authors: Jaakkola, E, Herzberg, I, Laiho, K, Barnardo, M C N M, Pointon, J J, Kauppi, M, Kaarela, K, Tuomilehto‐Wolf, E, Tuomilehto, J, Wordsworth, B P, Brown, M A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Extended Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798178/
https://ncbi.nlm.nih.gov/pubmed/16249228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2005.041103
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