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Evaluation of Susceptibility of Human Herpesvirus 8 to Antiviral Drugs by Quantitative Real-Time PCR

A new in vitro system based on real-time PCR was developed for evaluation of human herpesvirus 8 susceptibility to antiviral agents. Cidofovir had the greatest inhibitory activity against HHV-8 (50% inhibitory concentration [IC(50)], 0.43 μM) followed by ganciclovir (2.61 μM), adefovir (18.00 μM), a...

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Bibliografiske detaljer
Udgivet i:J Clin Microbiol
Principais autores: Sergerie, Yan, Boivin, Guy
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179795/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12904413/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JCM.41.8.3897-3900.2003
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