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Evaluation of Susceptibility of Human Herpesvirus 8 to Antiviral Drugs by Quantitative Real-Time PCR

A new in vitro system based on real-time PCR was developed for evaluation of human herpesvirus 8 susceptibility to antiviral agents. Cidofovir had the greatest inhibitory activity against HHV-8 (50% inhibitory concentration [IC(50)], 0.43 μM) followed by ganciclovir (2.61 μM), adefovir (18.00 μM), a...

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Bibliographic Details
Main Authors: Sergerie, Yan, Boivin, Guy
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC179795/
https://ncbi.nlm.nih.gov/pubmed/12904413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.41.8.3897-3900.2003
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