Genomic Analysis of Mycobacterium tuberculosis Complex Strains Used for Production of Purified Protein Derivative

The genomes of the tuberculin production strains Mycobacterium bovis AN5 and Mycobacterium tuberculosis DT were compared to genome-sequenced tubercle bacilli by using DNA microarrays. Neither the AN5 nor DT strain suffered extensive gene deletions during in vitro passage. This suggests that bovine t...

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Detalhes bibliográficos
Main Authors: Inwald, Jacqueline, Hinds, Jason, Palmer, Si, Dale, James, Butcher, Philip D., Hewinson, R. Glyn, Gordon, Stephen V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC179793/
https://ncbi.nlm.nih.gov/pubmed/12904421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.41.8.3929-3932.2003
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