Genomic Analysis of Mycobacterium tuberculosis Complex Strains Used for Production of Purified Protein Derivative

The genomes of the tuberculin production strains Mycobacterium bovis AN5 and Mycobacterium tuberculosis DT were compared to genome-sequenced tubercle bacilli by using DNA microarrays. Neither the AN5 nor DT strain suffered extensive gene deletions during in vitro passage. This suggests that bovine t...

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Autores principales: Inwald, Jacqueline, Hinds, Jason, Palmer, Si, Dale, James, Butcher, Philip D., Hewinson, R. Glyn, Gordon, Stephen V.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Mycobacteriology and Aerobic Actinomycetes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC179793/
https://ncbi.nlm.nih.gov/pubmed/12904421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.41.8.3929-3932.2003
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