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Genomic Analysis of Mycobacterium tuberculosis Complex Strains Used for Production of Purified Protein Derivative

The genomes of the tuberculin production strains Mycobacterium bovis AN5 and Mycobacterium tuberculosis DT were compared to genome-sequenced tubercle bacilli by using DNA microarrays. Neither the AN5 nor DT strain suffered extensive gene deletions during in vitro passage. This suggests that bovine t...

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Auteurs principaux: Inwald, Jacqueline, Hinds, Jason, Palmer, Si, Dale, James, Butcher, Philip D., Hewinson, R. Glyn, Gordon, Stephen V.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC179793/
https://ncbi.nlm.nih.gov/pubmed/12904421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.41.8.3929-3932.2003
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