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Genomic Analysis of Mycobacterium tuberculosis Complex Strains Used for Production of Purified Protein Derivative

The genomes of the tuberculin production strains Mycobacterium bovis AN5 and Mycobacterium tuberculosis DT were compared to genome-sequenced tubercle bacilli by using DNA microarrays. Neither the AN5 nor DT strain suffered extensive gene deletions during in vitro passage. This suggests that bovine t...

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Main Authors: Inwald, Jacqueline, Hinds, Jason, Palmer, Si, Dale, James, Butcher, Philip D., Hewinson, R. Glyn, Gordon, Stephen V.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC179793/
https://ncbi.nlm.nih.gov/pubmed/12904421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.41.8.3929-3932.2003
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