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Lead and δ-Aminolevulinic Acid Dehydratase Polymorphism: Where Does It Lead? A Meta-Analysis

BACKGROUND: Lead poisoning affects many organs in the body. Lead inhibits δ-aminolevulinic acid dehydratase (ALAD), an enzyme with two co-dominantly expressed alleles, ALAD1 and ALAD2. OBJECTIVE: Our meta-analysis studied the effects of the ALAD polymorphism on a) blood and bone lead levels and b) i...

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Bibliographic Details
Main Authors: Scinicariello, Franco, Murray, H. Edward, Moffett, Daphne B., Abadin, Henry G., Sexton, Mary J., Fowler, Bruce A.
Format: Artigo
Language:Inglês
Published: National Institute of Environmental Health Sciences 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797830/
https://ncbi.nlm.nih.gov/pubmed/17366816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.9448
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