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An Unmethylated 3′ Promoter-Proximal Region Is Required for Efficient Transcription Initiation
The promoter regions of approximately 40% of genes in the human genome are embedded in CpG islands, CpG-rich regions that frequently extend on the order of one kb 3′ of the transcription start site (TSS) region. CpGs 3′ of the TSS of actively transcribed CpG island promoters typically remain methyla...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1797817/ https://ncbi.nlm.nih.gov/pubmed/17305432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030027 |
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