An Unmethylated 3′ Promoter-Proximal Region Is Required for Efficient Transcription Initiation

The promoter regions of approximately 40% of genes in the human genome are embedded in CpG islands, CpG-rich regions that frequently extend on the order of one kb 3′ of the transcription start site (TSS) region. CpGs 3′ of the TSS of actively transcribed CpG island promoters typically remain methyla...

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Detaylı Bibliyografya
Asıl Yazarlar: Appanah, Ruth, Dickerson, David R, Goyal, Preeti, Groudine, Mark, Lorincz, Matthew C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797817/
https://ncbi.nlm.nih.gov/pubmed/17305432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030027
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