Protection of Mice from Lethal Escherichia coli Infection by Chimeric Human Bactericidal/Permeability-Increasing Protein and Immunoglobulin G1 Fc Gene Delivery

To evaluate the potentiality of applying gene therapy to bacterial infections, especially for preventing infection in high-risk patients, we investigated protection of mice from challenge with lethal Escherichia coli infection by adeno-associated virus serotype 2 (AAV2)-mediated gene transfer of a c...

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Detalhes bibliográficos
Main Authors: Chen, Jindong, Li, Chengyao, Guan, Yuanzhi, Kong, Qingli, Li, Chen, Guo, Xianghua, Chen, Qinghua, Jing, Xuefang, Lv, Zhe, An, Yunqing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797731/
https://ncbi.nlm.nih.gov/pubmed/17145792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00360-06
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