Posaconazole Prophylaxis in Experimental Systemic Zygomycosis

Three isolates of zygomycetes belonging to two different genera (Rhizopus oryzae and Absidia corymbifera) were used to produce a systemic infection in neutropenic mice. On days −2 and −1 and at 2 h prior to infection, the mice received either posaconazole (POS) at doses ranging from 20 to 80 mg/kg o...

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Autors principals: Barchiesi, Francesco, Spreghini, Elisabetta, Santinelli, Alfredo, Fothergill, Annette W., Pisa, Eleonora, Giannini, Daniele, Rinaldi, Michael G., Scalise, Giorgio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797686/
https://ncbi.nlm.nih.gov/pubmed/17060525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00969-06
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