MUC1 Induced by Epstein-Barr Virus Latent Membrane Protein 1 Causes Dissociation of the Cell-Matrix Interaction and Cellular Invasiveness via STAT Signaling

Disruption of cellular adhesion is an essential pathobiologic step leading to tumor dissemination. Mucin 1 (MUC1) is a mucinous glycoprotein expressed at the surfaces of epithelial cells in many tissues and their carcinomas. MUC1 plays crucial roles in tumor invasion and metastasis, especially in op...

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Detalhes bibliográficos
Main Authors: Kondo, Satoru, Yoshizaki, Tomokazu, Wakisaka, Naohiro, Horikawa, Toshiyuki, Murono, Shigeyuki, Jang, Kyung Lib, Joab, Irene, Furukawa, Mitsuru, Pagano, Joseph S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797593/
https://ncbi.nlm.nih.gov/pubmed/17151127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02222-06
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