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Inner membrane efflux components are responsible for beta-lactam specificity of multidrug efflux pumps in Pseudomonas aeruginosa.

A major feature of the MexAB-OprM multidrug efflux pump which distinguishes it from the MexCD-OprJ and MexEF-OprN multidrug efflux systems in Pseudomonas aeruginosa is its ability to export a wide variety of beta-lactam antibiotics. Given the periplasmic location of their targets it is feasible that...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Srikumar, R, Li, X Z, Poole, K
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179755/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9401051/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.24.7875-7881.1997
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