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Inhibition of the Secretory Pathway by Foot-and-Mouth Disease Virus 2BC Protein Is Reproduced by Coexpression of 2B with 2C, and the Site of Inhibition Is Determined by the Subcellular Location of 2C

Infection of cells with picornaviruses can lead to a block in protein secretion. For poliovirus this is achieved by the 3A protein, and the consequent reduction in secretion of proinflammatory cytokines and surface expression of major histocompatibility complex class I proteins may inhibit host immu...

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Detalhes bibliográficos
Main Authors: Moffat, Katy, Knox, Caroline, Howell, Gareth, Clark, Sarah J., Yang, H., Belsham, Graham J., Ryan, Martin, Wileman, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797538/
https://ncbi.nlm.nih.gov/pubmed/17121791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00393-06
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