Not All Cytokine-Producing CD8(+) T Cells Suppress Simian Immunodeficiency Virus Replication

Current assays of CD8(+) T-lymphocyte function measure cytokine production rather than the ability of these lymphocytes to suppress viral replication. Here we show that CD8(+) T-cell clones recognizing the same epitope vary enormously in the ability to suppress simian immunodeficiency virus SIVmac23...

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Autores principales: Chung, Chungwon, Lee, Wonhee, Loffredo, John T., Burwitz, Benjamin, Friedrich, Thomas C., Giraldo Vela, Juan Pablo, Napoe, Gnankang, Rakasz, Eva G., Wilson, Nancy A., Allison, David B., Watkins, David I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797528/
https://ncbi.nlm.nih.gov/pubmed/17135324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01780-06
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