GB Virus B Disrupts RIG-I Signaling by NS3/4A-Mediated Cleavage of the Adaptor Protein MAVS

Understanding the mechanisms of hepatitis C virus (HCV) pathogenesis and persistence has been hampered by the lack of small, convenient animal models. GB virus B (GBV-B) is phylogenetically the closest related virus to HCV. It causes generally acute and occasionally chronic hepatitis in small primat...

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Detalhes bibliográficos
Main Authors: Chen, Zihong, Benureau, Yann, Rijnbrand, Rene, Yi, Jianzhong, Wang, Ting, Warter, Lucile, Lanford, Robert E., Weinman, Steven A., Lemon, Stanley M., Martin, Annette, Li, Kui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797450/
https://ncbi.nlm.nih.gov/pubmed/17093192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02076-06
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