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High-Affinity Binding of the Staphylococcal HarA Protein to Haptoglobin and Hemoglobin Involves a Domain with an Antiparallel Eight-Stranded β-Barrel Fold

Iron scavenging from the host is essential for the growth of pathogenic bacteria. In this study, we further characterized two staphylococcal cell wall proteins previously shown to bind hemoproteins. HarA and IsdB harbor homologous ligand binding domains, the so called NEAT domain (for “near transpor...

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Autors principals: Dryla, Agnieszka, Hoffmann, Bernd, Gelbmann, Dieter, Giefing, Carmen, Hanner, Markus, Meinke, Andreas, Anderson, Annaliesa S., Koppensteiner, Walter, Konrat, Robert, von Gabain, Alexander, Nagy, Eszter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797202/
https://ncbi.nlm.nih.gov/pubmed/17041047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01366-06
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