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Mutational analysis of amiloride sensitivity of the NhaA Na+/H+ antiporter from Vibrio parahaemolyticus.

The activity of the NhaA Na+/H+ antiporter of Vibrio parahaemolyticus is inhibited by amiloride. We found an amino acid sequence in the NhaA that was identical to a putative amiloride binding domain of the Na+/H+ exchanger in mammalian cells. We constructed mutant NhaAs that had amino acid substitut...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Kuroda, T, Shimamoto, T, Mizushima, T, Tsuchiya, T
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179717/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9393731/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.23.7600-7602.1997
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