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Mutational analysis of amiloride sensitivity of the NhaA Na+/H+ antiporter from Vibrio parahaemolyticus.

The activity of the NhaA Na+/H+ antiporter of Vibrio parahaemolyticus is inhibited by amiloride. We found an amino acid sequence in the NhaA that was identical to a putative amiloride binding domain of the Na+/H+ exchanger in mammalian cells. We constructed mutant NhaAs that had amino acid substitut...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kuroda, T, Shimamoto, T, Mizushima, T, Tsuchiya, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC179717/
https://ncbi.nlm.nih.gov/pubmed/9393731
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