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Lytic Activity of Recombinant Bacteriophage φ11 and φ12 Endolysins on Whole Cells and Biofilms of Staphylococcus aureus

The recombinant φ11 endolysin hydrolyzed heat-killed staphylococci as well as staphylococcal biofilms. Cell wall targeting appeared to be a prerequisite for lysis of whole cells, and the combined action of the endopeptidase and amidase domains was necessary for maximum activity. In contrast, the φ12...

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Detalhes bibliográficos
Main Authors: Sass, Peter, Bierbaum, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797112/
https://ncbi.nlm.nih.gov/pubmed/17085695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01616-06
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