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The lack of a functional p21(WAF1/CIP1) gene ameliorates progression to chronic renal failure

Partial renal ablation leads to progressive renal insufficiency and is a model of chronic renal failure from diverse causes. We find that mice develop functional and morphologic characteristics of chronic renal failure after partial renal ablation, including glomerular sclerosis, systemic hypertensi...

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Detalhes bibliográficos
Main Authors: Megyesi, Judit, Price, Peter M., Tamayo, Esther, Safirstein, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17968/
https://ncbi.nlm.nih.gov/pubmed/10485911
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