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Novel c-MYC target genes mediate differential effects on cell proliferation and migration

The developmental and oncogenic roles of MYC proteins are well established, but the transcriptional targets mediating their functions remain elusive. Using small interfering RNA-mediated knockdown in breast and cervix carcinoma cell lines, which overexpress c-MYC, we show that c-MYC independently co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cappellen, David, Schlange, Thomas, Bauer, Matthieu, Maurer, Francisca, Hynes, Nancy E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796762/
https://ncbi.nlm.nih.gov/pubmed/17159920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400849
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