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Pin1 stabilizes Emi1 during G2 phase by preventing its association with SCF(βtrcp)

The anaphase-promoting complex (APC) early mitotic inhibitor 1 (Emi1) is required to induce S- and M-phase entries by stimulating the accumulation of cyclin A and cyclin B through APC(Cdh1/cdc20) inhibition. In this report, we show that Emi1 proteolysis can be induced by cyclin A/cdk (cdk for cyclin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bernis, Cyril, Vigneron, Suzanne, Burgess, Andrew, Labbé, Jean-Claude, Fesquet, Didier, Castro, Anna, Lorca, Thierry
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796751/
https://ncbi.nlm.nih.gov/pubmed/17159919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400853
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