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Pin1 stabilizes Emi1 during G2 phase by preventing its association with SCF(βtrcp)
The anaphase-promoting complex (APC) early mitotic inhibitor 1 (Emi1) is required to induce S- and M-phase entries by stimulating the accumulation of cyclin A and cyclin B through APC(Cdh1/cdc20) inhibition. In this report, we show that Emi1 proteolysis can be induced by cyclin A/cdk (cdk for cyclin...
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Glavni autori: | , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2007
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1796751/ https://ncbi.nlm.nih.gov/pubmed/17159919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400853 |
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