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FlowerPower: clustering proteins into domain architecture classes for phylogenomic inference of protein function

BACKGROUND: Function prediction by transfer of annotation from the top database hit in a homology search has been shown to be prone to systematic error. Phylogenomic analysis reduces these errors by inferring protein function within the evolutionary context of the entire family. However, accuracy of...

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Detalhes bibliográficos
Principais autores: Krishnamurthy, Nandini, Brown, Duncan, Sjölander, Kimmen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796606/
https://ncbi.nlm.nih.gov/pubmed/17288570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-7-S1-S12
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