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FlowerPower: clustering proteins into domain architecture classes for phylogenomic inference of protein function

BACKGROUND: Function prediction by transfer of annotation from the top database hit in a homology search has been shown to be prone to systematic error. Phylogenomic analysis reduces these errors by inferring protein function within the evolutionary context of the entire family. However, accuracy of...

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書目詳細資料
Main Authors: Krishnamurthy, Nandini, Brown, Duncan, Sjölander, Kimmen
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796606/
https://ncbi.nlm.nih.gov/pubmed/17288570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-7-S1-S12
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